This study was conducted to identify reasons for a high and progressive loss to follow-up among HIV-positive mothers within a prevention-of-mother-to-child HIV transmission (PMTCT) program in a rural district hospital in Malawi. Three focus group discussions were conducted among a total of 25 antenatal and post-natal mothers as well as nurse midwives (median age 39 years, range 22–55 years). The main reasons for loss to follow-up included: not being prepared for HIV testing and its implications before the antenatal clinic (ANC) visit; fear of stigma, discrimination, household conflict and even divorce on disclosure of HIV status; lack of support from husbands who do not want to undergo HIV testing; the feeling that one is obliged to rely on artificial feeding, which is associated with social and cultural taboos; long waiting times at the ANC; and inability to afford transport costs related to the long distances to the hospital. This study reveals a number of community- and provider-related operational and cultural barriers hindering the overall acceptability of PMTCT that need to be addressed urgently. Mothers attending antenatal services need to be better informed and supported, at both community and health-provider level.
Equity and HIV/AIDS
This study assessed the role of governmental and non-governmental organisations in mitigation of stigma and discrimination among people infected and affected by HIV/AIDS in informal settlements of Kibera. More than 61% of the respondents had patients in their households. Fifty-five percent (55%) of the households received assistance from governmental and non-governmental organisations in taking care of the sick. Services provided included awareness, outreach, counselling, testing, treatment, advocacy, home based care, assistance to the orphans and legal issues. About 90% of the respondents perceived health education, counselling services and formation of post counselling support groups to combat stigma and discrimination to be helpful. Stigma and discrimination affects the rights of People Living with HIV/AIDS (PLWHAs). Such stigmatisation and discrimination goes beyond and affects those who care for the PLWHAs, and remains the biggest impediment in the fight against HIV/AIDS in Kibera. Governmental and non-governmental organizations continue to provide key services in the mitigation of stigma and discrimination in Kibera. However, personal testimonies by PLWHAs showed that HIV positive persons still suffer from stigma and discrimination. About 43% of the study population experienced stigma and discrimination.
HIV/AIDS treatment guidelines for South Africa's public health sector are out of sync not only with those of many other countries in the region, but also with the latest research on how to most effectively treat people living with HIV. Various studies indicating that patients who start antiretroviral therapy (ART) earlier respond better to treatment and are less likely to develop AIDS-related illnesses have led the United States, the United Kingdom and a number of countries in Africa to change their treatment protocols. Deciding when to start a patient on life-long ARV drugs is usually based on a combination of CD4 cell count test results [which indicate the strength of the immune system] and HIV disease progression, which the World Health Organisation (WHO) has defined according to four clinical stages, with stage four being AIDS. The WHO revised its guidelines in 2003 to recommend that a patient who has reached stage three of the disease and has a CD4 count of less than 350 should begin treatment. Most countries in the region have revised their guidelines accordingly, but South Africa's national ART guidelines are still based on earlier WHO recommendations that ART be prescribed only for patients with stage four disease, or a CD4 count of less than 200. In April, the Southern African HIV Clinicians Society published guidelines in the Southern African Journal of HIV Medicine recommending that people living with HIV begin ART when their CD4 cell count drops below 350, regardless of disease progression. These guidelines are endorsed by the region's leading HIV specialists but have no direct influence on the South African government's ART programme.
Since the beginning of the HIV epidemic, governments have prevented people living with HIV from entering or residing in their countries based solely on their HIV status. Such restrictions have stopped HIV positive people from travelling for business, family visits, or tourism; and from entering a country for study, labour migration, and political asylum. Seldom is HIV testing linked to any treatment, heath care, counselling or support, either in country of origin or destination. Nor are the results necessarily kept confidential. Though countries focus on excluding HIV positive migrants, little is done to protect migrants from HIV infection while in destination countries – and indeed some do get infected. There have also been reports of HIV-positive migrants dying for lack of treatment while abroad, including in immigration detention facilities pending deportation. HIV-travel restrictions are anachronisms that are inappropriate in the age of globalisation, increased travel, increased access to treatment for HIV, and national and international commitments to universal access to HIV prevention, treatment, care and support. They are also discriminatory and contribute to stigmatisation. No evidence suggests that HIV-related travel restrictions protect the public health, and they may in fact impede efforts to stop the epidemic. UNAIDS recognizes that States impose immigration and visa restrictions as a valid exercise of their national sovereignty. However, in imposing any restrictions on entry and stay relating to HIV or health, UNAIDS calls upon States to adopt non-discriminatory laws and regulations which rationally achieve valid objectives through the least restrictive means possible.
UNAIDS, in collaboration the World Food Programme (WFP) and the World Health Organization (WHO), has developed a policy brief on HIV, food security and nutrition. This policy provides guidance for governments, civil society and other partners on how to address food and nutrition concerns in the context of HIV, keeping in mind the commitment made by all UN member states through the Millennium Development Goals both to reduce chronic hunger and halt and reverse the spread of HIV by 2015.
Based on interviews in two South African provinces and extensive consultation with South African agencies involved with the issue, this report provides a detailed portrait of the situation of rural women, and the interaction among violence, poverty, and the risk of HIV/AIDS. The overview has a concise survey of the development of the AIDS epidemic in South Africa including the debates about government policy and the active role of civil society.
Few sub-Saharan African countries have substantial analyses of the rural and agricultural situations in their Poverty Reduction Strategy Papers (PRSPs) and the link between agriculture and HIV and AIDS is therefore missed. Rural poverty is at the root of risky behavior (sexual services for food, cash or other resources), which can often lead to an HIV infection, hence the rate of HIV transmission can only be effectively reduced by reducing rural poverty. The report recommends improvements in agriculture, food supply, local social security networks (which provide information and behavioural advice) and access to assets that can be mobilised as alternatives to transactional sex. Gender issues also need to be addressed.
By 31 December 2006, Malawi had enrolled 82 000 patients in its free national antiretroviral treatment (ART) programme. Each quarter, data from all ART clinics are aggregated for national reporting on ART scale-up. This information is essential to monitoring site performance, guiding national planning and supporting sustained funding. Despite increasing reliance on sites to aggregate data, the completeness and accuracy of sites’ reports was unknown. The authors therefore conducted an operational study during regular supervisory visits to assess the quality of data in the site reports. Specific objectives were to: i) determine the completeness and accuracy of key case registration and outcome data compiled by ART clinics, ii) compare national data summarized from site reports versus supervision reports, and iii) analyse characteristics associated with sites’ capacity to compile quality data.
This paper describes the experience of Zimbabwe in establishing a baseline for its National Action Plan for Orphans and Other Vulnerable Children (NAP for OVC) using the 10 core indicators developed by the UNAIDS Global Monitoring and Evaluation Reference Group in 2004. Through a population-based household survey in rural and urban high-density areas and the OVC policy and planning effort index assessment tool, a baseline was established. The survey found that 43.6% of children under 18 years were orphaned or made vulnerable by HIV/AIDS. Half of all households with children care for one or more OVC. While the large majority of OVC continued to be cared for by the extended family, its capacity to care for these children appeared to be under pressure. OVC were less likely to have their basic minimum material needs met, more likely to be underweight, less likely to be taken to an appropriate health provider when sick and less likely to attend school. Medical support to households with OVC was found to be relatively high (26%). Other support, such as psychosocial support (2%) and school assistance (12%), was lower. The OVC Effort Index assessment indicates that serious efforts are being made. The increase in the effort index between 2001 and 2004 in the areas of consultative efforts, planning and coordinating mechanisms reflects the strengthened commitment. Monitoring and evaluation and legislative review are the weakest areas of the OVC response. The findings of the baseline exercise point to the need for continued and additional efforts and resources to implement the NAP for OVC, the priorities of which were confirmed by the survey as critical to improve the welfare of the OVC in Zimbabwe.
The diagnosis and management of childhood tuberculosis (TB) are major challenges in countries such as Malawi with high incidence of TB and human immunodeficiency virus (HIV) infection. Diagnosis of TB in children often relies only on clinical features but clinical overlap with the presentation of HIV and other HIV-related lung disease is common. The tuberculin skin test (TST), the standard marker of M. tuberculosis infection in immune competent children, has poor sensitivity in HIV-infected children and is not usually available in Malawi. HIV test should be routine in children with suspected TB as it improves clinical management. HIV-infected children are at increased risk of developing active disease following TB exposure which justifies the use of isoniazid preventive therapy (IPT) once active disease has been excluded but this is difficult to implement and appropriate duration of IPT is unknown. HIV-infected children with active TB experience higher mortality and relapse rates on standard TB treatment compared to HIV-uninfected children, highlighting the need for further research to define optimal treatment regimens. HIV-infected children should also receive appropriate supportive care including co-trimoxazole prophylaxis and anti-retroviral treatment (ART) if indicated. There are concerns about concurrent use of some anti-TB drugs such as rifampicin with some ARTs.