The non-profit Universities Allied for Essential Medicines (UAEM) is a student-driven movement to promote equitable global access and innovation in publicly funded medical research. Through UAEM’s advocacy, universities that license medical research to industry have now begun to include requirements for generic production or “at cost” provisions for low- and middle-income countries. These “global access” provisions lower the price of the final products for poor patients, and have been adopted by leading institutions including Harvard, Yale, the University of British Columbia, and the US National Institutes for Health (NIH). While over 30 research institutions worldwide have endorsed a “Statement of Principles and Strategies” supporting global access to their medical discoveries, the students of UAEM want to ensure that this translates into real-world impact. They argue that the statement itself should be strengthened, and individual universities can adopt more robust policies. Most importantly, however, universities must demonstrate that they are regularly including global access provisions in their licensing negotiations with pharmaceutical companies. Improving the transparency of universities and their licensing practices is critical. Not only do universities need to ensure affordable access to their medical breakthroughs, but they also need to show that they are committing resources, both human and financial, to research on neglected diseases.
Monitoring equity and research policy
Canadian occupational health and infection control researchers have found that training is key to a positive safety culture, leading them to develop information and communication technology (ICT) tools to promote occupational health and infection control. The South African government invited the Canadian team to work with local colleagues, resulting in an improved web-based health information system to track incidents, exposures, and occupational injury and diseases, just in time for the H1N1 pandemic. Research from these experiences led to strengthened focus on building capacity of health and safety committees, and new modules are thus being created, informed by that work. The international collaboration between occupational health and infection control researchers in Canada, Ecuador and South Africa led to the improvement of the research framework and development of tools, guidelines and information systems. Furthermore, the research and knowledge-transfer experience highlighted the value of partnership amongst Northern and Southern researchers in terms of sharing resources, experiences and knowledge.
This supplement of BMC International Health and Human Rights consists of a collection of 10 case studies showcasing effective global health research. The collection provides practical, transferable lessons for research partnerships working to address health inequities. In the context of increasing competition for individual or institutional "leadership" of the field (and business) of global health, these papers instead speak of active and sustained collaboration - listening, responsiveness, flexibility, willingness and capacity to follow as well as to lead - in learning what to transform or sustain, and how, in order to move towards greater equity in both health and health research. In addition, they challenge conventional models of research focused on narrowly defined research questions and a narrow range of pre-specified research methods, documenting instead how both the research questions and the methods most appropriate to address them change over time. Finally, they challenge both the idea of "pure" science undertaken by independent researchers on behalf of science and specific communities, and the conventional wisdom that North-South and research-research user-community partnerships are necessarily either North and researcher-driven, or scientifically dubious.
This paper explores the current situation in universities with respect to research practice. The author observes that the market-driven model is dominant in African universities. The consultancy culture it has nurtured has had negative consequences for postgraduate education and research. Consultants presume that research is all about finding answers to problems defined by a client. They think of research as finding answers, not as formulating a problem. The consultancy culture is institutionalized
through short courses in research methodology, courses that teach students
a set of tools to gather and process quantitative information, from which
to cull answers. The author calls in contrast for an intellectual environment strong enough to sustain a meaningful intellectual culture.
Unless African governments increase their funding for and engagement in HIV research, the continent cannot hope to attain equal status in determining its research agenda and priorities, speakers said at the 16th International Conference on AIDS and Sexually Transmitted Infections (STIs) in Africa, held in December 2011 in Ethiopia. Most African health research is driven by external funders, which often means that research starts and ends on the say-so of the funders, rather than being based on a country's needs. Prof Nelson Sewankambo, principal of the College of Health Sciences at Uganda's Makerere University, said heavy external funder involvement in local research can actually harm existing national institutions, which may lose strategic direction and become retarded by the loss of key staff to research projects and distortion of institutional structures and governance. He argued that inequities in collaboration can lead to lack of transparency in the decision-making process, as well as disputes over publication rights, ownership of data, specimens and equipment. Other speakers also noted that inadequate community engagement was common when partnerships were skewed in favour of funders’ priorities and ethical violations occurred in research projects, such as the use of placebos in studies on mother-to-child HIV transmission. They called for new, more equitable partnership models and expansion of local capacity to sustain research activities once externally funded projects ended.
In the context of recent global calls for strengthening the field of health policy and systems research (HPSR) as a critical input to strengthening health systems, the authors of this paper assessed the extent to which progress has been achieved in this regard. Two sources of data were used: a bibliometric analysis to assess growth in production of HPSR between 2003 and 2009, and a 2010 survey of 96 research institutions to assess capacity and funding availability to undertake HPSR. Both analyses focused on HPSR relevant to low-income and middle-income countries (LMICs). Overall, the authors found an increasing trend of publications on HPSR in LMICs, although only 4% were led by authors from low-income countries (LICs). Improvements were noted in infrastructure of research institutions in LICs, but more limited gains in the level of experience of researchers within institutions. There has been only a modest increase in availability of funding for LICs.
This is the third of a series of three papers addressing the current challenges and opportunities for the development of Health Policy and Systems Research (HPSR). The authors of this paper assert that there is an urgent need to build the Health Policy and Systems Research (HPSR) field and in particular to develop understanding across different disciplinary boundaries. The development of HPSR is impeded by a cluster of related issues: a heavy reliance on international funding for HPSR; an excessive focus on the direct utility of HPSR findings from specific studies; and a tendency to under-value contributions to HPSR from social sciences. Innovations in funding HPSR are needed so that local actors, including policy-makers, civil society, and researchers, have a greater say in determining the nature of HPSR conducted. Strategic investment should be made in promoting a greater shared understanding of theoretical frames and methodological approaches for HPSR including, for example, the development of HPSR journals, methodological workshops, and shared HPSR teaching curricula. Dedicated and supportive homes for HPSR need to be found within universities, and also be developed as independent research institutes, the authors conclude.
This is the first of a series of three papers addressing the current challenges and opportunities for the development of Health Policy and Systems Research (HPSR). HPSR is a multidisciplinary and interdisciplinary field identified by the topics and scope of questions asked rather than by methodology. The focus of discussion is HPSR in low- and middle-income countries. Topics of research in HPSR include international, national, and local health systems and their interconnectivities, and policies made and implemented at all levels of the health system. Research questions in HPSR vary by the level of analysis (macro, meso, and micro) and intent of the question (normative/evaluative or exploratory/explanatory). Current heightened attention on HPSR contains significant opportunities, but also threats in the form of certain focus areas and questions being privileged over others; “disciplinary capture” of the field by the dominant health research traditions; and premature and inappropriately narrow definitions. The authors call for greater attention to fundamental, exploratory, and explanatory types of HPSR; to the significance of the field for societal and national development, necessitating HPSR capacity building in low- and middle-income countries; and for greater literacy and application of a wide spectrum of methodologies.
This is the second of a series of three papers addressing the current challenges and opportunities for the development of Health Policy and Systems Research (HPSR). According to this paper, all researchers hold a knowledge paradigm that frames their understanding of reality and of the functions and nature of research. Some disciplines are dominated by a particular paradigm and some are spread across paradigms. The criticisms that Health Policy and Systems Research (HPSR) is too context specific, does not offer clear lessons for policy makers, and is not rigorous are partly a reflection of differences in knowledge paradigms between those with predominantly clinical, biomedical, and epidemiological backgrounds, underpinned by a positivist paradigm, and those with social science backgrounds underpinned by a relativist paradigm. Health policies and systems are complex social and political phenomena, constructed by human action rather than naturally occurring. Therefore, the authors argue, relativist social science perspectives are of particular relevance to HPSR as they recognise that all phenomena are in essence constructed through human behaviour and interpretation. Social science insights that can advance the science of HPSR include: approaches to generalising from rich understanding of context; supporting policy learning; and enhancing research rigour and quality.
In South Africa, the number of papers produced in health and rehabilitation sciences is insignificant compared with other health-related disciplines, according to the authors of this paper. To identify strategies to increase the number of these papers, the authors reviewed published papers that examined the effectiveness of interventions designed to promote research publications among academics and clinicians in health and rehabilitation sciences programmes. Seven of the papers reported on interventions for academics, and six reported on the interventions for academics in the nursing profession. The most common interventions were ‘writing support groups’, ‘writing retreats’, and ‘writing courses’ that lasted from three days to five years. The interventions were designed to meet the needs of the participants for structured time, motivation, improved writing skills and peer support. All the interventions produced significant research output relating to submission or publication of academic papers. The implementation of these interventions by South African tertiary institutions where health and rehabilitation sciences are offered may improve the number of papers published by the health research community, the authors conclude.